Motivated by prevention, diagnosis and treatment of degenerative diseases the research of the musculoskeletal biomechanics group focuses on multi-scale structure-function relationships of bone from the extracellular matrix to the organ level. Combined theoretical, experimental, and numerical approaches are applied to model, validate and simulate the mechanical behaviour of bone tissue and bone-implant systems in the course of growth, ageing, disease and treatment. The group provides also biomechanical testing services and cooperates with local, national as well as international partners from academia, hospitals and industry to help reduce the burden of bone diseases and failure of the bone-implant interface.